Toujeo vs Lantus: Main Differences and S Dulera vs Advair: Main Differences and S Suboxone vs Methadone: Main Differences Looking for a prescription? Search now! Type your drug name. Yes, famotidine. Yes, ranitidine.
Oral tablet Oral capsule Oral powder for suspension Oral solution Oral syrup. Pepcid Price. Zantac Price. Pepcid is in Pregnancy Category B. In the followups during 2 and 6 weeks after medical therapy, no side effects due to medical therapy were seen. Children with abdominal pain were found to miss more school than their peers, and their parents frequently missed work to take care of their children [ 6 ].
Some studies in children have shown an association between chronic or recurrent abdominal pain and higher depression and anxiety scores and poor quality of life [ 6 ]. Despite its high frequency and significant impact on quality of life of children, there is only limited evidence to support most treatments that are commonly used to treat childhood FAP.
Dietary recommendations may be helpful for some patients with functional recurrent abdominal pain of childhood [ 7 ]. There are different medical therapies with different medications for treatment of this disorder in children. Such therapy should be individualized and directed toward the predominant symptom [ 8 ].
Treatment modalities include medications, diet modification, herbal preparations, and behaviorally psychologic interventions [ 9 ]. Enteric-coated peppermint-oil capsules, believed to exert calcium channel blockade in smooth muscle, were shown in a randomized, placebo-controlled study to decrease the severity of abdominal pain, but not other symptoms in pediatric patients with irritable bowel syndrome [ 9 ].
Pharmacotherapy for treatment of FGIDs consists of anticholinergic agents, tricyclic antidepressants, serotonergic agents, selective serotonin reuptake inhibitors, 5-HT 3 receptor antagonists, 5-HT4 receptor agonists, and acid suppressive therapy [ 5 ]. For patients with predominant dyspepsia discomfort centered in the epigastrium, nausea, early satiety, postprandial fullness, recurrent emesis , a short course of empiric therapy with H 2 -receptor antagonists or proton pump inhibitors is acceptable [ 5 ].
Some meta-analysis studies showed that H 2 -receptor antagonists did or did not have a significant therapeutic effect in FD [ 10 , 11 ]. A meta-analysis of randomized controlled clinical trials has shown that there may be a benefit in the use of H 2 -receptor antagonists in patients suffering from FD [ 12 ]. In another study, it was found that Famotidine was equally effective as placebo [ 6 ]. In a double-blind randomized placebo-controlled study of 4 weeks of Lansoprazole a proton pump inhibitor for the treatment of FD in Chinese patients, findings implicated that proton pump inhibitors treatment was not superior to placebo for the management of FD in Chinese patients [ 15 ].
Proton pump inhibitors especially improved the symptoms of epigastric pain and heart burn [ 1 ]. Several studies in the primary care setting have concluded that proton pump inhibitors are more effective than H 2 -receptor antagonists or antacids in treating heart burn and dyspeptic symptoms [ 16 ].
Therefore, empiric acid suppression would seem to be the favored management approach for the treatment of FD [ 17 ].
Since the various proton pump inhibitors are of equivalent efficacy and safety, the cost and acceptability of a particular proton pump inhibitor preparation may be more important when selecting among them than comparable efficacy [ 18 ]. In this study, we compared the effectiveness of four medications including Cimetidine, Famotidine, Ranitidine all of them H 2 -receptor antagonists , and Omeprazole a proton pump inhibitor , for treatment of children with dyspeptic symptoms, to find the best one for this reason.
According to our results and the fact that no significant side effects being detected, and also due to the fact that Ranitidine and Omeprazole were the most effective medications on only one of the symptoms epigastric pain comparing with Omeprazole that had the best result on all symptoms being relieved, it cannot be concluded that Ranitidine and Famotidine have equal or better effect in treatment of FD, but, in fact, the best medical therapy for treatment of FD is Omeprazole, or in another way Omeprazole is superior to H 2 -receptor antagonists for treatment of FD.
At the end it is important to note that since 3 of 4 medications that we used in our study had approximately an equivalent efficacy and safety, the cost of a particular medication may be more important, when selecting among them, than comparable efficacy.
This is an open access article distributed under the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Article of the Year Award: Outstanding research contributions of , as selected by our Chief Editors. Read the winning articles. A Erratum for this article has been published. Academic Editor: A. Received 13 Jan Accepted 01 Mar Published 05 Apr Abstract Background.
Introduction Functional dyspepsia FD is a very common cause of upper gastrointestinal symptoms and discomfort [ 1 ]. Patients and Methods In this clinical trial study, children between 2 and 16 years old were enrolled with the diagnosis of FD which was made by a history of recurrent or persistent abdominal pain and discomfort which was typically centered in the upper abdomen for at least a week duration without any evidence of organic disorder.
Results There were children with various dyspeptic symptoms who participated in this study. A single nocturnal dose of 20 mg is effective in preventing duodenal ulcer relapse.
Further studies are required that compare the efficacy of famotidine with cimetidine and ranitidine in the treatment of gastric ulcers and in the prevention of recurrent duodenal ulcers. The overall incidence of adverse effects observed with famotidine appears to be similar to that reported for cimetidine and ranitidine. Omeprazole tends to have more warnings and precautions associated with it compared to famotidine.
Unlike famotidine, omeprazole and other PPIs can increase the risk of osteoporosis and bone fractures when used long term. Omeprazole use, especially in a hospital setting, may lead to an increased risk of Clostridium difficile related diarrhea.
One study found that proton pump inhibitors are associated with more risks of serious adverse effects like pneumonia and C. The study took data from 71 hospitals and assessed PPI and H2-blocker use in a specific population of patients.
Famotidine is an H2 blocker medication that is used to treat GERD, duodenal ulcers, and stomach ulcers. It is also FDA-approved to treat hypersecretory conditions like Zollinger-Ellison syndrome in adults. Famotidine is the generic form of Pepcid and is usually taken twice daily. It is also used to treat H. It is often taken once daily for four to eight weeks. Famotidine and omeprazole are not the same.
Although they treat similar gastrointestinal problems, they are different drugs. Famotidine is an H2 blocker and omeprazole is a PPI. Omeprazole is considered a more effective drug when compared to famotidine. Omeprazole lasts longer in the body with effects that increase after taking it every day. This cumulative effect is not seen with famotidine. However, omeprazole may have more adverse effects associated with its use.
Famotidine may have less risk of causing harm during pregnancy compared to omeprazole. Consult your healthcare provider when choosing a treatment option while pregnant or breastfeeding. Famotidine should be avoided with alcohol. Drinking alcohol while taking famotidine can increase the risk of CNS effects like confusion or drowsiness. Omeprazole may be fine to take with alcohol in moderation. However, mixing medications with alcohol should be avoided when possible, especially if you notice an increase in side effects.
Everyone responds to medications differently. Therefore, the safest acid reflux medicine is the one that works best for you with the least amount of side effects.
When compared to famotidine, omeprazole may have an increased risk of adverse effects , such as osteoporosis, especially when used long term. Pepcid is typically taken on a daily basis for up to six, eight, or 12 weeks at a time.
The duration of treatment depends on the condition that is being treated.
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